Complex 8cgv
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 1.66 |
| System mass | 1332.80 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 8cgv |
| Reference | Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN. 2023. Pending: 10.1038/s41594-023-01047-y |
| Equivalence Class |
NR_all_83717.185
BGSU version: 4.48 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | MUL |
| Residue | . / 3003 |
| Chain | GA / a |
| Non-redundant | True |
| Interacting RNA chains | E/a |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | E/a: rRNA |
| RNA family global | rRNA |
| Volume | 463.39 Å3 |
| Hydrophobicity | 0.897 |
| Hydrophilicity | 0.812 |
| Buriedness | 0.774 |
| Don/acc character | 1.661 |
| SiteScore | 1.180 |
| D Score | 1.056 |
| Kd | — |
| Compound | P8F |
| Residue | . / 3001 |
| Chain | EA / a |
| Non-redundant | True |
| Interacting RNA chains | E/a |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | E/a: rRNA |
| RNA family global | rRNA |
| Volume | 626.66 Å3 |
| Hydrophobicity | 0.209 |
| Hydrophilicity | 1.239 |
| Buriedness | 0.713 |
| Don/acc character | 1.567 |
| SiteScore | 1.160 |
| D Score | 0.964 |
| Kd | — |
| Compound | P8F |
| Residue | . / 3002 |
| Chain | FA / a |
| Non-redundant | True |
| Interacting RNA chains | E/a |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | E/a: rRNA |
| RNA family global | rRNA |
| Volume | 170.13 Å3 |
| Hydrophobicity | 0.168 |
| Hydrophilicity | 1.574 |
| Buriedness | 0.695 |
| Don/acc character | 0.798 |
| SiteScore | 0.953 |
| D Score | 0.594 |
| Kd | — |