Complex 8bf5
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.96 |
| System mass | 281.40 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Betainfluenzavirus |
| RCSB PDB Entry | 8bf5 |
| Reference | Kouba Tomas, Dubankova Anna, Drncova Petra, Donati Elisa, Vidossich Pietro, Speranzini Valentina, Pflug Alex, Huchting Johanna, Meier Chris, De Vivo Marco, Cusack Stephen. 2023. Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106 Cell Reports |
| Equivalence Class |
NR_all_01894.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | G2P |
| Residue | . / 801 |
| Chain | H / B |
| Non-redundant | True |
| Interacting RNA chains | F/M, E/R |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/R: unknown, F/M: mRNA |
| RNA family global | mRNA |
| Volume | 244.90 Å3 |
| Hydrophobicity | 0.537 |
| Hydrophilicity | 1.471 |
| Buriedness | 0.882 |
| Don/acc character | 0.559 |
| SiteScore | 0.903 |
| D Score | 0.707 |
| Kd | — |