Complex 7u2a
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 4.10 |
| System mass | 129.67 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 7u2a |
| Reference | Kuhle Bernhard, Hirschi Marscha, Doerfel Lili K., Lander Gabriel C., Schimmel Paul. 2022. Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA Nature Communications |
| Equivalence Class |
NR_all_49428.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SSA |
| Residue | . / 601 |
| Chain | D / A |
| Non-redundant | True |
| Interacting RNA chains | A/C |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/C: tRNA |
| RNA family global | tRNA |
| Volume | 374.90 Å3 |
| Hydrophobicity | 0.738 |
| Hydrophilicity | 1.436 |
| Buriedness | 0.929 |
| Don/acc character | 0.781 |
| SiteScore | 1.154 |
| D Score | 1.029 |
| Kd | — |