Complex 7ryf
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.65 |
| System mass | 2162.70 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Acinetobacter |
| RCSB PDB Entry | 7ryf |
| Reference | Morgan Christopher E., Zhang Zhemin, Bonomo Robert A., Yu Edward W.. 2022. An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii mBio |
| Equivalence Class |
NR_all_43481.6
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 80P |
| Residue | . / 1601 |
| Chain | CB / a |
| Non-redundant | True |
| Interacting RNA chains | EA/a |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | EA/a: rRNA |
| RNA family global | rRNA |
| Volume | 178.70 Å3 |
| Hydrophobicity | 0.050 |
| Hydrophilicity | 1.220 |
| Buriedness | 0.665 |
| Don/acc character | 4.215 |
| SiteScore | 0.562 |
| D Score | 0.525 |
| Kd | — |
| Compound | 80P |
| Residue | . / 1602 |
| Chain | DB / a |
| Non-redundant | True |
| Interacting RNA chains | EA/a |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | EA/a: rRNA |
| RNA family global | rRNA |
| Volume | 181.10 Å3 |
| Hydrophobicity | 0.423 |
| Hydrophilicity | 0.976 |
| Buriedness | 0.723 |
| Don/acc character | 3.725 |
| SiteScore | 0.656 |
| D Score | 0.680 |
| Kd | — |
| Compound | 80P |
| Residue | . / 1603 |
| Chain | EB / a |
| Non-redundant | True |
| Interacting RNA chains | EA/a |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | EA/a: rRNA |
| RNA family global | rRNA |
| Volume | 225.35 Å3 |
| Hydrophobicity | 0.191 |
| Hydrophilicity | 1.216 |
| Buriedness | 0.772 |
| Don/acc character | 3.032 |
| SiteScore | 0.858 |
| D Score | 0.527 |
| Kd | — |