HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 7pib

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 4.70
System mass 2361.00 kDa
Deposition year 2021
Molecule type RNA/Protein
# RNA entities 1
Organism Mycoplasmoides
RCSB PDB Entry 7pib
Reference Xue Liang, Lenz Swantje, Zimmermann-Kogadeeva Maria, Tegunov Dimitry, Cramer Patrick, Bork Peer, Rappsilber Juri, Mahamid Julia. 2022. Visualizing translation dynamics at atomic detail inside a bacterial cell Nature
Equivalence Class NR_all_01186.4
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SCM
Residue . / 1601
Chain EB / 5
Non-redundant True
Interacting RNA chains BB/5
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains BB/5: rRNA
RNA family global rRNA
Volume 601.62 Å3
Hydrophobicity 0.081
Hydrophilicity 1.136
Buriedness 0.767
Don/acc character 2.565
SiteScore 1.196
D Score 1.030
Kd