Complex 7o1a
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.40 |
| System mass | 2179.64 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 7o1a |
| Reference | van der Stel Anne-Xander, Gordon Emily R., Sengupta Arnab, Martínez Allyson K., Klepacki Dorota, Perry Thomas N., Herrero del Valle Alba, Vázquez-Laslop Nora, Sachs Matthew S., Cruz-Vera Luis R., Innis C. Axel. 2021. Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling Nature Communications |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | TRP |
| Residue | . / 3001 |
| Chain | ZF / BA |
| Non-redundant | True |
| Interacting RNA chains | V/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | V/BA: rRNA |
| RNA family global | rRNA |
| Volume | 416.06 Å3 |
| Hydrophobicity | 0.466 |
| Hydrophilicity | 1.296 |
| Buriedness | 0.803 |
| Don/acc character | 1.041 |
| SiteScore | 1.070 |
| D Score | 1.000 |
| Kd | — |