Complex 7l0z
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.10 |
| System mass | 23.64 kDa |
| Deposition year | 2020 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7l0z |
| Reference | Jeng Sunny C.Y., Trachman Robert J., Weissenboeck Florian, Truong Lynda, Link Katie A., Jepsen Mette D.E., Knutson Jay R., Andersen Ebbe S., Ferré-D'Amaré Adrian R., Unrau Peter J.. 2021. Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET RNA |
| Equivalence Class |
NR_all_57264.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 2ZY |
| Residue | . / 101 |
| Chain | B / G |
| Non-redundant | True |
| Interacting RNA chains | A/G |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | A/G: aptamer_rna |
| RNA family global | aptamer_rna |
| Volume | 152.98 Å3 |
| Hydrophobicity | 0.811 |
| Hydrophilicity | 0.955 |
| Buriedness | 0.640 |
| Don/acc character | 1.965 |
| SiteScore | 0.902 |
| D Score | 0.819 |
| Kd | — |
| Compound | SPM |
| Residue | . / 102 |
| Chain | C / G |
| Non-redundant | True |
| Interacting RNA chains | A/G |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/G: aptamer_rna |
| RNA family global | aptamer_rna |
| Volume | 125.88 Å3 |
| Hydrophobicity | 0.018 |
| Hydrophilicity | 1.060 |
| Buriedness | 0.643 |
| Don/acc character | 3.117 |
| SiteScore | 0.814 |
| D Score | 0.597 |
| Kd | — |
| Compound | SPM |
| Residue | . / 103 |
| Chain | D / G |
| Non-redundant | True |
| Interacting RNA chains | A/G |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/G: aptamer_rna |
| RNA family global | aptamer_rna |
| Volume | 31.56 Å3 |
| Hydrophobicity | 0.000 |
| Hydrophilicity | 0.867 |
| Buriedness | 0.475 |
| Don/acc character | 1.427 |
| SiteScore | 0.481 |
| D Score | 0.233 |
| Kd | — |
| Compound | SPM |
| Residue | . / 104 |
| Chain | E / G |
| Non-redundant | True |
| Interacting RNA chains | A/G |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/G: aptamer_rna |
| RNA family global | aptamer_rna |
| Volume | 256.91 Å3 |
| Hydrophobicity | 0.065 |
| Hydrophilicity | 0.980 |
| Buriedness | 0.689 |
| Don/acc character | 2.987 |
| SiteScore | 0.881 |
| D Score | 0.681 |
| Kd | — |