Complex 6qit
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.50 |
| System mass | 12.26 kDa |
| Deposition year | 2019 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 6qit |
| Reference | Mukherjee Sanjukta, Błaszczyk Leszek, Rypniewski Wojciech, Falschlunger Christoph, Micura Ronald, Murata Asako, Dohno Chikara, Nakatani Kazuhiko, Kiliszek Agnieszka. 2019. Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats Nucleic Acids Research |
| Equivalence Class |
NR_all_99409.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | J48 |
| Residue | . / 101 |
| Chain | E / A |
| Non-redundant | False |
| Interacting RNA chains | B/B, A/A |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: unknown, B/B: unknown |
| RNA family global | unknown |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | J48 |
| Residue | . / 102 |
| Chain | F / A |
| Non-redundant | False |
| Interacting RNA chains | B/B, A/A |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: unknown, B/B: unknown |
| RNA family global | unknown |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | J48 |
| Residue | . / 101 |
| Chain | G / C |
| Non-redundant | False |
| Interacting RNA chains | D/D, C/C |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | C/C: unknown, D/D: unknown |
| RNA family global | unknown |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | J48 |
| Residue | . / 101 |
| Chain | H / D |
| Non-redundant | False |
| Interacting RNA chains | D/D, C/C |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | C/C: unknown, D/D: unknown |
| RNA family global | unknown |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |