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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 6g7z

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.34
System mass 60.21 kDa
Deposition year 2018
Molecule type RNA
# RNA entities 1
Organism Didymium
RCSB PDB Entry 6g7z
Reference Meyer Mélanie, Walbott Hélène, Oliéric Vincent, Kondo Jiro, Costa Maria, Masquida Benoît. 2019. Conformational adaptation of UNCG loops upon crowding RNA
Equivalence Class NR_all_57460.6
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound MES
Residue . / 201
Chain E / B
Non-redundant False
Interacting RNA chains B/B
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains B/B: ribozyme
RNA family global ribozyme
Volume 130.34 Å3
Hydrophobicity 0.403
Hydrophilicity 0.918
Buriedness 0.691
Don/acc character 2.670
SiteScore 0.844
D Score 0.639
Kd