Complex 6bsj
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.89 |
| System mass | 131.38 kDa |
| Deposition year | 2017 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 6bsj |
| Reference | Tian Lan, Kim Min-Sung, Li Hongzhi, Wang Jimin, Yang Wei. 2018. Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_20621.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | TAM |
| Residue | . / 101 |
| Chain | K / R |
| Non-redundant | True |
| Interacting RNA chains | D/R |
| RNA environment detailled | DNA |
| RNA environment global | RNA/DNA |
| RNA family chains | D/R: TAR_rna |
| RNA family global | TAR_rna |
| Volume | 88.49 Å3 |
| Hydrophobicity | 0.099 |
| Hydrophilicity | 0.629 |
| Buriedness | 0.492 |
| Don/acc character | 3.288 |
| SiteScore | 1.092 |
| D Score | 1.030 |
| Kd | — |