Complex 6bfb
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.82 |
| System mass | 36.00 kDa |
| Deposition year | 2017 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Fusobacterium |
| RCSB PDB Entry | 6bfb |
| Reference | Rizvi Noreen F., Howe John A., Nahvi Ali, Klein Daniel J., Fischmann Thierry O., Kim Hai-Young, McCoy Mark A., Walker Scott S., Hruza Alan, Richards Matthew P., Chamberlin Chad, Saradjian Peter, Butko Margaret T., Mercado Gabriel, Burchard Julja, Strickland Corey, Dandliker Peter J., Smith Graham F., Nickbarg Elliott B.. 2018. Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry ACS Chemical Biology |
| Equivalence Class |
NR_all_63890.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | DKM |
| Residue | . / 500 |
| Chain | C / X |
| Non-redundant | True |
| Interacting RNA chains | B/Y, A/X |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/X: riboswitch, B/Y: riboswitch |
| RNA family global | riboswitch |
| Volume | 930.56 Å3 |
| Hydrophobicity | 0.385 |
| Hydrophilicity | 1.315 |
| Buriedness | 0.791 |
| Don/acc character | 0.842 |
| SiteScore | 1.212 |
| D Score | 0.986 |
| Kd | — |