Complex 6az4
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.98 |
| System mass | 13.94 kDa |
| Deposition year | 2017 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 6az4 |
| Reference | Zhang Wen, Tam Chun Pong, Zhou Lijun, Oh Seung Soo, Wang Jiawei, Szostak Jack W.. 2018. Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide Journal of the American Chemical Society |
| Equivalence Class |
NR_all_96856.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GP3 |
| Residue | . / 101 |
| Chain | C / A |
| Non-redundant | False |
| Interacting RNA chains | B/B, A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: synthetic construct, B/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 114.22 Å3 |
| Hydrophobicity | 0.055 |
| Hydrophilicity | 0.620 |
| Buriedness | 0.453 |
| Don/acc character | 1.732 |
| SiteScore | 1.067 |
| D Score | 1.010 |
| Kd | — |