HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 4v8q

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.10
System mass 2348.30 kDa
Deposition year 2011
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 4v8q
Reference Neubauer Cajetan, Gillet Reynald, Kelley Ann C., Ramakrishnan V.. 2012. Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome Science
Equivalence Class NR_all_97519.80
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GDP
Residue . / 1003
Chain OB / BZ
Non-redundant True
Interacting RNA chains K/AA
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains K/AA: rRNA
RNA family global rRNA
Volume 450.70 Å3
Hydrophobicity 0.041
Hydrophilicity 1.734
Buriedness 0.703
Don/acc character 0.689
SiteScore 1.003
D Score 0.796
Kd