Complex 4v8o
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.80 |
| System mass | 2292.76 kDa |
| Deposition year | 2011 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4v8o |
| Reference | Jin Hong, Kelley Ann C., Ramakrishnan V.. 2011. Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GCP |
| Residue | . / 1000 |
| Chain | FB / AY |
| Non-redundant | True |
| Interacting RNA chains | IA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | IA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 724.76 Å3 |
| Hydrophobicity | 0.142 |
| Hydrophilicity | 1.584 |
| Buriedness | 0.774 |
| Don/acc character | 1.214 |
| SiteScore | 1.051 |
| D Score | 0.888 |
| Kd | — |