Complex 4v7y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.00 |
| System mass | 4267.39 kDa |
| Deposition year | 2010 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4v7y |
| Reference | Bulkley David, Innis C. Axel, Blaha Gregor, Steitz Thomas A.. 2010. Revisiting the structures of several antibiotics bound to the bacterial ribosome Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ZIT |
| Residue | . / 3351 |
| Chain | QS / BA |
| Non-redundant | True |
| Interacting RNA chains | EA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | EA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 707.61 Å3 |
| Hydrophobicity | 0.306 |
| Hydrophilicity | 1.422 |
| Buriedness | 0.744 |
| Don/acc character | 0.985 |
| SiteScore | 1.180 |
| D Score | 0.923 |
| Kd | — |
| Compound | ZIT |
| Residue | . / 3311 |
| Chain | IHA / DA |
| Non-redundant | True |
| Interacting RNA chains | DC/DA |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | DC/DA: rRNA |
| RNA family global | rRNA |
| Volume | 696.98 Å3 |
| Hydrophobicity | 0.400 |
| Hydrophilicity | 1.382 |
| Buriedness | 0.748 |
| Don/acc character | 0.937 |
| SiteScore | 1.184 |
| D Score | 0.938 |
| Kd | — |