Complex 4v7x
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.00 |
| System mass | 4267.87 kDa |
| Deposition year | 2010 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4v7x |
| Reference | Bulkley David, Innis C. Axel, Blaha Gregor, Steitz Thomas A.. 2010. Revisiting the structures of several antibiotics bound to the bacterial ribosome Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ERY |
| Residue | . / 3364 |
| Chain | FT / BA |
| Non-redundant | True |
| Interacting RNA chains | EA/BA |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | EA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 1200.84 Å3 |
| Hydrophobicity | 0.481 |
| Hydrophilicity | 0.816 |
| Buriedness | 0.642 |
| Don/acc character | 0.794 |
| SiteScore | 1.156 |
| D Score | 1.059 |
| Kd | — |
| Compound | ERY |
| Residue | . / 3330 |
| Chain | TIA / DA |
| Non-redundant | True |
| Interacting RNA chains | DC/DA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | DC/DA: rRNA |
| RNA family global | rRNA |
| Volume | 737.11 Å3 |
| Hydrophobicity | 0.559 |
| Hydrophilicity | 1.329 |
| Buriedness | 0.757 |
| Don/acc character | 0.958 |
| SiteScore | 1.190 |
| D Score | 0.961 |
| Kd | — |