Complex 4v64
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.50 |
| System mass | 4296.89 kDa |
| Deposition year | 2008 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 4v64 |
| Reference | Borovinskaya Maria A., Shoji Shinichiro, Fredrick Kurt, Cate Jamie H.D.. 2008. Structural basis for hygromycin B inhibition of protein biosynthesis RNA |
| Equivalence Class |
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | HYG |
| Residue | . / 2059 |
| Chain | GF / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 88.84 Å3 |
| Hydrophobicity | 0.268 |
| Hydrophilicity | 0.671 |
| Buriedness | 0.685 |
| Don/acc character | 1.871 |
| SiteScore | 0.659 |
| D Score | 0.423 |
| Kd | — |
| Compound | HYG |
| Residue | . / 2062 |
| Chain | ZL / CA |
| Non-redundant | True |
| Interacting RNA chains | AB/CA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 115.25 Å3 |
| Hydrophobicity | 0.349 |
| Hydrophilicity | 0.853 |
| Buriedness | 0.697 |
| Don/acc character | 2.138 |
| SiteScore | 0.684 |
| D Score | 0.438 |
| Kd | — |