Complex 4v5r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.10 |
| System mass | 4666.52 kDa |
| Deposition year | 2010 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4v5r |
| Reference | Schmeing T Martin, Voorhees Rebecca M, Kelley Ann C, Ramakrishnan V. 2011. How mutations in tRNA distant from the anticodon affect the fidelity of decoding Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GDP |
| Residue | . / 501 |
| Chain | QD / AZ |
| Non-redundant | True |
| Interacting RNA chains | KA/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | KA/BA: rRNA |
| RNA family global | rRNA |
| Volume | 327.57 Å3 |
| Hydrophobicity | 0.186 |
| Hydrophilicity | 1.316 |
| Buriedness | 0.713 |
| Don/acc character | 0.936 |
| SiteScore | 1.010 |
| D Score | 0.938 |
| Kd | — |