Complex 4v57
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.50 |
| System mass | 4298.30 kDa |
| Deposition year | 2007 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 4v57 |
| Reference | Borovinskaya Maria A., Shoji Shinichiro, Holton James M., Fredrick Kurt, Cate Jamie H. D.. 2007. A Steric Block in Translation Caused by the Antibiotic Spectinomycin ACS Chemical Biology |
| Equivalence Class |
NR_all_83717.187,
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | NMY |
| Residue | . / 1601 |
| Chain | AD / AA |
| Non-redundant | False |
| Interacting RNA chains | A/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 157.09 Å3 |
| Hydrophobicity | 0.218 |
| Hydrophilicity | 0.937 |
| Buriedness | 0.652 |
| Don/acc character | 2.903 |
| SiteScore | 0.979 |
| D Score | 0.820 |
| Kd | — |
| Compound | NMY |
| Residue | . / 3001 |
| Chain | KF / BB |
| Non-redundant | False |
| Interacting RNA chains | W/BB, A/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA, W/BB: rRNA |
| RNA family global | rRNA |
| Volume | 239.07 Å3 |
| Hydrophobicity | 0.184 |
| Hydrophilicity | 0.794 |
| Buriedness | 0.626 |
| Don/acc character | 2.139 |
| SiteScore | 0.957 |
| D Score | 0.781 |
| Kd | — |
| Compound | NMY |
| Residue | . / 1601 |
| Chain | SJ / CA |
| Non-redundant | True |
| Interacting RNA chains | AB/CA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 177.67 Å3 |
| Hydrophobicity | 0.180 |
| Hydrophilicity | 0.976 |
| Buriedness | 0.665 |
| Don/acc character | 2.613 |
| SiteScore | 1.012 |
| D Score | 0.856 |
| Kd | — |
| Compound | NMY |
| Residue | . / 3001 |
| Chain | BM / DB |
| Non-redundant | True |
| Interacting RNA chains | WB/DB, AB/CA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA, WB/DB: rRNA |
| RNA family global | rRNA |
| Volume | 151.61 Å3 |
| Hydrophobicity | 0.171 |
| Hydrophilicity | 0.635 |
| Buriedness | 0.644 |
| Don/acc character | 2.593 |
| SiteScore | 0.787 |
| D Score | 0.600 |
| Kd | — |
| Compound | SCM |
| Residue | . / 1662 |
| Chain | JF / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 441.78 Å3 |
| Hydrophobicity | 0.098 |
| Hydrophilicity | 1.121 |
| Buriedness | 0.732 |
| Don/acc character | 2.522 |
| SiteScore | 1.173 |
| D Score | 1.013 |
| Kd | — |
| Compound | SCM |
| Residue | . / 1661 |
| Chain | AM / CA |
| Non-redundant | True |
| Interacting RNA chains | AB/CA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | AB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 452.07 Å3 |
| Hydrophobicity | 0.089 |
| Hydrophilicity | 1.156 |
| Buriedness | 0.718 |
| Don/acc character | 1.756 |
| SiteScore | 1.163 |
| D Score | 0.994 |
| Kd | — |