Complex 4v52
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.21 |
| System mass | 4297.71 kDa |
| Deposition year | 2007 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 4v52 |
| Reference | Borovinskaya Maria A, Pai Raj D, Zhang Wen, Schuwirth Barbara S, Holton James M, Hirokawa Go, Kaji Hideko, Kaji Akira, Cate Jamie H Doudna. 2007. Structural basis for aminoglycoside inhibition of bacterial ribosome recycling Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_83717.187,
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | NMY |
| Residue | . / 1601 |
| Chain | AD / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 160.18 Å3 |
| Hydrophobicity | 0.108 |
| Hydrophilicity | 1.000 |
| Buriedness | 0.632 |
| Don/acc character | 4.482 |
| SiteScore | 0.910 |
| D Score | 0.731 |
| Kd | — |
| Compound | NMY |
| Residue | . / 3001 |
| Chain | JF / BB |
| Non-redundant | True |
| Interacting RNA chains | A/AA, W/BB |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA, W/BB: rRNA |
| RNA family global | rRNA |
| Volume | 176.99 Å3 |
| Hydrophobicity | 0.073 |
| Hydrophilicity | 1.112 |
| Buriedness | 0.596 |
| Don/acc character | 1.504 |
| SiteScore | 0.667 |
| D Score | 0.698 |
| Kd | — |
| Compound | NMY |
| Residue | . / 1601 |
| Chain | RJ / CA |
| Non-redundant | True |
| Interacting RNA chains | AB/CA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 178.02 Å3 |
| Hydrophobicity | 0.167 |
| Hydrophilicity | 0.928 |
| Buriedness | 0.647 |
| Don/acc character | 3.605 |
| SiteScore | 0.928 |
| D Score | 0.757 |
| Kd | — |
| Compound | NMY |
| Residue | . / 3001 |
| Chain | CM / DB |
| Non-redundant | True |
| Interacting RNA chains | AB/CA, WB/DB |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA, WB/DB: rRNA |
| RNA family global | rRNA |
| Volume | 180.76 Å3 |
| Hydrophobicity | 0.056 |
| Hydrophilicity | 1.167 |
| Buriedness | 0.644 |
| Don/acc character | 1.434 |
| SiteScore | 0.844 |
| D Score | 0.600 |
| Kd | — |