Complex 4v4h
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.46 |
| System mass | 4301.00 kDa |
| Deposition year | 2006 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 4v4h |
| Reference | Schuwirth Barbara S, Day J Michael, Hau Cathy W, Janssen Gary R, Dahlberg Albert E, Cate Jamie H Doudna, Vila-Sanjurjo Antón. 2006. Structural analysis of kasugamycin inhibition of translation Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_56726.172
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | KSG |
| Residue | . / 1601 |
| Chain | AD / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 420.86 Å3 |
| Hydrophobicity | 0.043 |
| Hydrophilicity | 1.386 |
| Buriedness | 0.714 |
| Don/acc character | 1.969 |
| SiteScore | 1.160 |
| D Score | 0.916 |
| Kd | — |
| Compound | KSG |
| Residue | . / 1601 |
| Chain | PJ / CA |
| Non-redundant | True |
| Interacting RNA chains | AB/CA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | AB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 369.75 Å3 |
| Hydrophobicity | 0.078 |
| Hydrophilicity | 1.394 |
| Buriedness | 0.695 |
| Don/acc character | 1.801 |
| SiteScore | 1.148 |
| D Score | 0.902 |
| Kd | — |