Complex 4nfo
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.96 |
| System mass | 15.50 kDa |
| Deposition year | 2013 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 4nfo |
| Reference | Phelps Kelly J., Ibarra-Soza José M., Tran Kiet, Fisher Andrew J., Beal Peter A.. 2014. Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA ACS Chemical Biology |
| Equivalence Class |
NR_all_10487.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SPM |
| Residue | . / 101 |
| Chain | D / C |
| Non-redundant | True |
| Interacting RNA chains | C/C, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: unknown, C/C: unknown |
| RNA family global | unknown |
| Volume | 60.03 Å3 |
| Hydrophobicity | 0.011 |
| Hydrophilicity | 0.519 |
| Buriedness | 0.402 |
| Don/acc character | 3.119 |
| SiteScore | 1.052 |
| D Score | 1.012 |
| Kd | — |