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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 4m30

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.50
System mass 70.63 kDa
Deposition year 2013
Molecule type RNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 4m30
Reference Court Donald L., Gan Jianhua, Liang Yu-He, Shaw Gary X., Tropea Joseph E., Costantino Nina, Waugh David S., Ji Xinhua. 2013. RNase III: Genetics and Function; Structure and Mechanism Annual Review of Genetics
Equivalence Class NR_all_52425.4
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound AMP
Residue . / 103
Chain L / C
Non-redundant True
Interacting RNA chains C/C, D/D
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains C/C: unknown, D/D: unknown
RNA family global unknown
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound AMP
Residue . / 104
Chain P / D
Non-redundant True
Interacting RNA chains C/C, D/D
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains C/C: unknown, D/D: unknown
RNA family global unknown
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd