Complex 4k32

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.50
System mass	15.71 kDa
Deposition year	2013
Molecule type	RNA
# RNA entities	1
Organism	Leishmania
RCSB PDB Entry	4k32
Reference	Shalev Moran, Kondo Jiro, Kopelyanskiy Dmitry, Jaffe Charles L., Adir Noam, Baasov Timor. 2013. Identification of the molecular attributes required for aminoglycoside activity against Leishmania Proceedings of the National Academy of Sciences
Equivalence Class	NR_all_71199.7 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	GET
Residue	. / 101
Chain	C / A
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	84.72 Å³
Hydrophobicity	0.078
Hydrophilicity	0.977
Buriedness	0.578
Don/acc character	1.122
SiteScore	0.795
D Score	0.600
Kd	—

Pocket 2

Compound	GET
Residue	. / 101
Chain	D / B
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	RNA-only
RNA environment global	RNA
RNA family chains	A/A: rRNA, B/B: rRNA
RNA family global	rRNA
Volume	50.42 Å³
Hydrophobicity	0.245
Hydrophilicity	0.982
Buriedness	0.574
Don/acc character	0.935
SiteScore	0.733
D Score	0.522
Kd	—