HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 4ji1

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.14
System mass 792.56 kDa
Deposition year 2013
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 4ji1
Reference Demirci Hasan, Wang Leyi, Murphy Frank V., Murphy Eileen L., Carr Jennifer F., Blanchard Scott C., Jogl Gerwald, Dahlberg Albert E., Gregory Steven T.. 2013. The central role of protein S12 in organizing the structure of the decoding site of the ribosome RNA
Equivalence Class NR_all_65795.87
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SRY
Residue . / 1601
Chain V / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains A/A: rRNA
RNA family global rRNA
Volume 180.76 Å3
Hydrophobicity 0.062
Hydrophilicity 1.507
Buriedness 0.801
Don/acc character 1.656
SiteScore 0.717
D Score 0.478
Kd