Complex 4ioc
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.60 |
| System mass | 1365.98 kDa |
| Deposition year | 2013 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Deinococcus |
| RCSB PDB Entry | 4ioc |
| Reference | Magee Thomas V., Han Seungil, McCurdy Sandra P., Nguyen Thuy-Trinh, Granskog Karl, Marr Eric S., Maguire Bruce A., Huband Michael D., Chen Jinshan Michael, Subashi Timothy A., Shanmugasundaram Veerabahu. 2013. Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates Bioorganic & Medicinal Chemistry Letters |
| Equivalence Class |
NR_all_88987.11
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 1F4 |
| Residue | . / 2929 |
| Chain | GB / X |
| Non-redundant | True |
| Interacting RNA chains | A/X |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/X: rRNA |
| RNA family global | rRNA |
| Volume | 326.88 Å3 |
| Hydrophobicity | 0.129 |
| Hydrophilicity | 1.196 |
| Buriedness | 0.780 |
| Don/acc character | 2.555 |
| SiteScore | 0.704 |
| D Score | 0.567 |
| Kd | — |