Complex 4gpw
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.00 |
| System mass | 15.67 kDa |
| Deposition year | 2012 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 4gpw |
| Reference | Kondo Jiro, Koganei Mai, Maianti Juan Pablo, Ly Vu Linh, Hanessian Stephen. 2013. Crystal Structures of a Bioactive 6′‐Hydroxy Variant of Sisomicin Bound to the Bacterial and Protozoal Ribosomal Decoding Sites ChemMedChem |
| Equivalence Class |
NR_all_71199.7
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 6HS |
| Residue | . / 101 |
| Chain | C / A |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 86.09 Å3 |
| Hydrophobicity | 0.370 |
| Hydrophilicity | 0.969 |
| Buriedness | 0.617 |
| Don/acc character | 1.344 |
| SiteScore | 0.834 |
| D Score | 0.641 |
| Kd | — |
| Compound | 6HS |
| Residue | . / 102 |
| Chain | D / A |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 81.63 Å3 |
| Hydrophobicity | 0.054 |
| Hydrophilicity | 1.058 |
| Buriedness | 0.550 |
| Don/acc character | 1.335 |
| SiteScore | 0.770 |
| D Score | 0.565 |
| Kd | — |