Complex 3pla
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.15 |
| System mass | 303.29 kDa |
| Deposition year | 2010 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 3pla |
| Reference | Lin Jinzhong, Lai Shaomei, Jia Ru, Xu Anbi, Zhang Liman, Lu Jing, Ye Keqiong. 2011. Structural basis for site-specific ribose methylation by box C/D RNA protein complexes Nature |
| Equivalence Class |
NR_all_83671.4
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAH |
| Residue | . / 301 |
| Chain | P / E |
| Non-redundant | False |
| Interacting RNA chains | G/G, I/I |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | G/G: synthetic construct, I/I: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 257.94 Å3 |
| Hydrophobicity | 0.799 |
| Hydrophilicity | 1.312 |
| Buriedness | 0.959 |
| Don/acc character | 0.795 |
| SiteScore | 1.174 |
| D Score | 1.088 |
| Kd | — |
| Compound | SAH |
| Residue | . / 301 |
| Chain | Q / F |
| Non-redundant | True |
| Interacting RNA chains | H/H, J/J |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | H/H: synthetic construct, J/J: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 262.05 Å3 |
| Hydrophobicity | 0.724 |
| Hydrophilicity | 1.360 |
| Buriedness | 0.960 |
| Don/acc character | 0.870 |
| SiteScore | 1.175 |
| D Score | 1.073 |
| Kd | — |
| Compound | SAH |
| Residue | . / 301 |
| Chain | R / M |
| Non-redundant | False |
| Interacting RNA chains | O/O, N/N |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | N/N: synthetic construct, O/O: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 253.82 Å3 |
| Hydrophobicity | 0.938 |
| Hydrophilicity | 1.377 |
| Buriedness | 0.963 |
| Don/acc character | 0.785 |
| SiteScore | 1.177 |
| D Score | 1.069 |
| Kd | — |