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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3ova

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 1.98
System mass 62.86 kDa
Deposition year 2010
Molecule type RNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 3ova
Reference Pan Baocheng, Xiong Yong, Steitz Thomas A.. 2010. How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA Science
Equivalence Class NR_all_65533.3
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound APC
Residue . / 501
Chain C / A
Non-redundant True
Interacting RNA chains B/C
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains B/C: tRNA
RNA family global tRNA
Volume 551.89 Å3
Hydrophobicity 0.120
Hydrophilicity 1.516
Buriedness 0.842
Don/acc character 0.622
SiteScore 1.096
D Score 0.951
Kd