Complex 3j7y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.40 |
| System mass | 1717.08 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 3j7y |
| Reference | Brown Alan, Amunts Alexey, Bai Xiao-chen, Sugimoto Yoichiro, Edwards Patricia C., Murshudov Garib, Scheres Sjors H. W., Ramakrishnan V.. 2014. Structure of the large ribosomal subunit from human mitochondria Science |
| Equivalence Class |
NR_all_12763.37
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | AMP |
| Residue | . / 3301 |
| Chain | ZA / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/A: rRNA |
| RNA family global | rRNA |
| Volume | 187.96 Å3 |
| Hydrophobicity | 0.128 |
| Hydrophilicity | 1.174 |
| Buriedness | 0.643 |
| Don/acc character | 1.772 |
| SiteScore | 0.948 |
| D Score | 0.731 |
| Kd | — |