Complex 3iwn
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.20 |
| System mass | 82.66 kDa |
| Deposition year | 2009 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Vibrio |
| RCSB PDB Entry | 3iwn |
| Reference | Kulshina Nadia, Baird Nathan J, Ferré-D'Amaré Adrian R. 2009. Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_25458.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | C2E |
| Residue | . / 501 |
| Chain | E / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 405.77 Å3 |
| Hydrophobicity | 0.577 |
| Hydrophilicity | 1.022 |
| Buriedness | 0.686 |
| Don/acc character | 1.614 |
| SiteScore | 1.145 |
| D Score | 1.018 |
| Kd | — |
| Compound | C2E |
| Residue | . / 601 |
| Chain | F / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 655.82 Å3 |
| Hydrophobicity | 0.402 |
| Hydrophilicity | 1.118 |
| Buriedness | 0.706 |
| Don/acc character | 1.058 |
| SiteScore | 1.155 |
| D Score | 0.999 |
| Kd | — |