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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3g96

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Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.01
System mass 245.05 kDa
Deposition year 2009
Molecule type RNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 3g96
Reference Cochrane Jesse C., Lipchock Sarah V., Smith Kathryn D., Strobel Scott A.. 2009. Structural and Chemical Basis for Glucosamine 6-Phosphate Binding and Activation of the glmS Ribozyme Biochemistry
Equivalence Class NR_all_17906.2
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound 6MN
Residue . / 12
Chain M / F
Non-redundant True
Interacting RNA chains F/Q, E/F
RNA environment detailled ion
RNA environment global RNA
RNA family chains E/F: ribozyme, F/Q: ribozyme
RNA family global ribozyme
Volume 404.05 Å3
Hydrophobicity 0.062
Hydrophilicity 1.892
Buriedness 0.742
Don/acc character 0.536
SiteScore 1.180
D Score 0.769
Kd