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HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3cc4

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.70
System mass 1493.53 kDa
Deposition year 2008
Molecule type RNA/Protein
# RNA entities 1
Organism Haloarcula
RCSB PDB Entry 3cc4
Reference Blaha Gregor, Gürel Güliz, Schroeder Susan J., Moore Peter B., Steitz Thomas A.. 2008. Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant Journal of Molecular Biology
Equivalence Class NR_all_26150.5
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound ANM
Residue . / 2924
Chain SL / 0
Non-redundant True
Interacting RNA chains DA/0
RNA environment detailled ion
RNA environment global RNA
RNA family chains DA/0: rRNA
RNA family global rRNA
Volume 515.53 Å3
Hydrophobicity 0.410
Hydrophilicity 1.000
Buriedness 0.740
Don/acc character 1.859
SiteScore 1.186
D Score 1.058
Kd