Complex 3c7r

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	1.70
System mass	16.23 kDa
Deposition year	2008
Molecule type	RNA/DNA
# RNA entities	1
Organism	N/A
RCSB PDB Entry	3c7r
Reference	Freisz Séverine, Lang Kathrin, Micura Ronald, Dumas Philippe, Ennifar Eric. 2008. Binding of Aminoglycoside Antibiotics to the Duplex Form of the HIV‐1 Genomic RNA Dimerization Initiation Site Angewandte Chemie International Edition
Equivalence Class	NR_all_30081.2 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	NMY
Residue	. / 24
Chain	C / A
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	A/A: TAR_rna, B/B: TAR_rna
RNA family global	TAR_rna
Volume	511.76 Å³
Hydrophobicity	0.074
Hydrophilicity	1.222
Buriedness	0.701
Don/acc character	1.551
SiteScore	1.152
D Score	0.962
Kd	—

Pocket 2

Compound	NMY
Residue	. / 24
Chain	E / B
Non-redundant	False
Interacting RNA chains	A/A, B/B
RNA environment detailled	other
RNA environment global	RNA/Other
RNA family chains	A/A: TAR_rna, B/B: TAR_rna
RNA family global	TAR_rna
Volume	453.45 Å³
Hydrophobicity	0.092
Hydrophilicity	1.184
Buriedness	0.701
Don/acc character	1.408
SiteScore	1.152
D Score	0.975
Kd	—