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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3amu

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.10
System mass 76.30 kDa
Deposition year 2010
Molecule type RNA/Protein
# RNA entities 1
Organism Archaeoglobus
RCSB PDB Entry 3amu
Reference Osawa Takuo, Kimura Satoshi, Terasaka Naohiro, Inanaga Hideko, Suzuki Tsutomu, Numata Tomoyuki. 2011. Structural basis of tRNA agmatinylation essential for AUA codon decoding Nature Structural & Molecular Biology
Equivalence Class NR_all_56041.3
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound APC
Residue . / 421
Chain C / A
Non-redundant True
Interacting RNA chains B/B
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains B/B: tRNA
RNA family global tRNA
Volume 757.69 Å3
Hydrophobicity 0.534
Hydrophilicity 1.265
Buriedness 0.781
Don/acc character 0.993
SiteScore 1.055
D Score 0.996
Kd