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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3al0

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.37
System mass 201.92 kDa
Deposition year 2010
Molecule type RNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 3al0
Reference Ito Takuhiro, Yokoyama Shigeyuki. 2010. Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions Nature
Equivalence Class NR_all_04935.5
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GSU
Residue . / 1001
Chain F / C
Non-redundant True
Interacting RNA chains D/E
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains D/E: tRNA
RNA family global tRNA
Volume 493.92 Å3
Hydrophobicity 0.555
Hydrophilicity 1.519
Buriedness 0.885
Don/acc character 0.452
SiteScore 1.125
D Score 0.976
Kd