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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 36le

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 1.73
System mass 22.67 kDa
Deposition year 2026
Molecule type RNA
# RNA entities 1
Organism N/A
RCSB PDB Entry 36le
Equivalence Class NR_all_01949.9
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound DGP
Residue . / 102
Chain F / A
Non-redundant True
Interacting RNA chains B/B, A/A
RNA environment detailled other
RNA environment global RNA/Other
RNA family chains A/A: synthetic construct, B/B: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 103
Chain G / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled other
RNA environment global RNA/Other
RNA family chains A/A: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 102
Chain I / B
Non-redundant True
Interacting RNA chains B/B, A/A
RNA environment detailled other
RNA environment global RNA/Other
RNA family chains A/A: synthetic construct, B/B: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 103
Chain J / B
Non-redundant True
Interacting RNA chains B/B
RNA environment detailled other
RNA environment global RNA/Other
RNA family chains B/B: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 102
Chain L / C
Non-redundant True
Interacting RNA chains D/D, C/C
RNA environment detailled ion, other
RNA environment global RNA/Other
RNA family chains C/C: synthetic construct, D/D: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 103
Chain M / C
Non-redundant True
Interacting RNA chains C/C
RNA environment detailled ion, other
RNA environment global RNA/Other
RNA family chains C/C: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 102
Chain Q / D
Non-redundant True
Interacting RNA chains D/D, C/C
RNA environment detailled ion, other
RNA environment global RNA/Other
RNA family chains C/C: synthetic construct, D/D: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound DGP
Residue . / 103
Chain R / D
Non-redundant True
Interacting RNA chains D/D
RNA environment detailled ion, other
RNA environment global RNA/Other
RNA family chains D/D: synthetic construct
RNA family global synthetic construct
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd