Complex 2zxu
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.75 |
| System mass | 119.95 kDa |
| Deposition year | 2009 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 2zxu |
| Reference | Chimnaronk Sarin, Forouhar Farhad, Sakai Junichi, Yao Min, Tron Cecile M., Atta Mohamed, Fontecave Marc, Hunt John F., Tanaka Isao. 2009. Snapshots of Dynamics in Synthesizing N6-Isopentenyladenosine at the tRNA Anticodon Biochemistry |
| Equivalence Class |
NR_all_19951.102
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | DST |
| Residue | . / 317 |
| Chain | E / A |
| Non-redundant | True |
| Interacting RNA chains | C/C |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | C/C: tRNA |
| RNA family global | tRNA |
| Volume | 264.80 Å3 |
| Hydrophobicity | 0.551 |
| Hydrophilicity | 1.662 |
| Buriedness | 0.929 |
| Don/acc character | 0.433 |
| SiteScore | 1.154 |
| D Score | 0.956 |
| Kd | — |