Complex 2yie
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.94 |
| System mass | 37.11 kDa |
| Deposition year | 2011 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Fusobacterium |
| RCSB PDB Entry | 2yie |
| Reference | Vicens Quentin, Mondragón Estefanía, Batey Robert T.. 2011. Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection Nucleic Acids Research |
| Equivalence Class |
NR_all_63890.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | FMN |
| Residue | . / 1114 |
| Chain | L / Z |
| Non-redundant | True |
| Interacting RNA chains | B/Z, A/X |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/X: riboswitch, B/Z: riboswitch |
| RNA family global | riboswitch |
| Volume | 987.15 Å3 |
| Hydrophobicity | 0.576 |
| Hydrophilicity | 1.309 |
| Buriedness | 0.798 |
| Don/acc character | 0.737 |
| SiteScore | 1.217 |
| D Score | 0.992 |
| Kd | — |