Complex 2rd2
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.60 |
| System mass | 88.79 kDa |
| Deposition year | 2007 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 2rd2 |
| Reference | Bullock Timothy L., Rodríguez-Hernández Annia, Corigliano Eleonora M., Perona John J.. 2008. A rationally engineered misacylating aminoacyl-tRNA synthetase Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_31819.8
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | QSI |
| Residue | . / 998 |
| Chain | E / A |
| Non-redundant | True |
| Interacting RNA chains | A/B |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/B: tRNA |
| RNA family global | tRNA |
| Volume | 518.62 Å3 |
| Hydrophobicity | 0.912 |
| Hydrophilicity | 1.312 |
| Buriedness | 0.827 |
| Don/acc character | 0.463 |
| SiteScore | 1.086 |
| D Score | 1.009 |
| Kd | — |