Complex 2qwy
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.80 |
| System mass | 52.52 kDa |
| Deposition year | 2007 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2qwy |
| Reference | Gilbert Sunny D, Rambo Robert P, Van Tyne Daria, Batey Robert T. 2008. Structure of the SAM-II riboswitch bound to S-adenosylmethionine Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_83080.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAM |
| Residue | . / 100 |
| Chain | H / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 442.47 Å3 |
| Hydrophobicity | 0.271 |
| Hydrophilicity | 0.894 |
| Buriedness | 0.663 |
| Don/acc character | 2.151 |
| SiteScore | 1.148 |
| D Score | 1.037 |
| Kd | — |
| Compound | SAM |
| Residue | . / 300 |
| Chain | K / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 386.56 Å3 |
| Hydrophobicity | 0.308 |
| Hydrophilicity | 0.871 |
| Buriedness | 0.622 |
| Don/acc character | 1.711 |
| SiteScore | 1.128 |
| D Score | 1.024 |
| Kd | — |
| Compound | SAM |
| Residue | . / 500 |
| Chain | O / C |
| Non-redundant | False |
| Interacting RNA chains | C/C |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | C/C: riboswitch |
| RNA family global | riboswitch |
| Volume | 397.54 Å3 |
| Hydrophobicity | 0.346 |
| Hydrophilicity | 0.852 |
| Buriedness | 0.670 |
| Don/acc character | 2.113 |
| SiteScore | 1.118 |
| D Score | 1.001 |
| Kd | — |