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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 2ogo

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.66
System mass 956.40 kDa
Deposition year 2007
Molecule type RNA/Protein
# RNA entities 1
Organism Deinococcus
RCSB PDB Entry 2ogo
Reference Davidovich Chen, Bashan Anat, Auerbach-Nevo Tamar, Yaggie Rachel D., Gontarek Richard R., Yonath Ada. 2007. Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity Proceedings of the National Academy of Sciences
Equivalence Class NR_all_88987.11
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound G34
Residue . / 0
Chain C / 0
Non-redundant True
Interacting RNA chains A/0
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains A/0: rRNA
RNA family global rRNA
Volume 533.02 Å3
Hydrophobicity 0.590
Hydrophilicity 0.997
Buriedness 0.795
Don/acc character 1.841
SiteScore 1.220
D Score 1.088
Kd