Complex 2nz4
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.50 |
| System mass | 244.40 kDa |
| Deposition year | 2006 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Bacillus |
| RCSB PDB Entry | 2nz4 |
| Reference | Cochrane Jesse C., Lipchock Sarah V., Strobel Scott A.. 2007. Structural Investigation of the GlmS Ribozyme Bound to Its Catalytic Cofactor Chemistry & Biology |
| Equivalence Class |
NR_all_17906.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GLP |
| Residue | . / 5001 |
| Chain | M / P |
| Non-redundant | True |
| Interacting RNA chains | A/E, B/P |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/E: ribozyme, B/P: ribozyme |
| RNA family global | ribozyme |
| Volume | 391.36 Å3 |
| Hydrophobicity | 0.131 |
| Hydrophilicity | 2.157 |
| Buriedness | 0.752 |
| Don/acc character | 0.527 |
| SiteScore | 1.186 |
| D Score | 0.688 |
| Kd | — |
| Compound | GLP |
| Residue | . / 5002 |
| Chain | R / F |
| Non-redundant | True |
| Interacting RNA chains | C/F, D/Q |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | C/F: ribozyme, D/Q: ribozyme |
| RNA family global | ribozyme |
| Volume | 579.33 Å3 |
| Hydrophobicity | 0.079 |
| Hydrophilicity | 1.998 |
| Buriedness | 0.776 |
| Don/acc character | 0.703 |
| SiteScore | 1.202 |
| D Score | 0.755 |
| Kd | — |
| Compound | GLP |
| Residue | . / 5003 |
| Chain | W / G |
| Non-redundant | True |
| Interacting RNA chains | F/R, E/G |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | E/G: ribozyme, F/R: ribozyme |
| RNA family global | ribozyme |
| Volume | 384.50 Å3 |
| Hydrophobicity | 0.102 |
| Hydrophilicity | 1.843 |
| Buriedness | 0.755 |
| Don/acc character | 0.514 |
| SiteScore | 1.188 |
| D Score | 0.793 |
| Kd | — |
| Compound | GLP |
| Residue | . / 5004 |
| Chain | BA / H |
| Non-redundant | True |
| Interacting RNA chains | G/H, H/S |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | G/H: ribozyme, H/S: ribozyme |
| RNA family global | ribozyme |
| Volume | 373.87 Å3 |
| Hydrophobicity | 0.136 |
| Hydrophilicity | 1.938 |
| Buriedness | 0.750 |
| Don/acc character | 0.597 |
| SiteScore | 1.185 |
| D Score | 0.758 |
| Kd | — |