Complex 2n0j
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Solution NMR |
| Experimental resolution | N/A |
| System mass | 9.01 kDa |
| Deposition year | 2015 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2n0j |
| Reference | Duchardt‐Ferner Elke, Gottstein‐Schmidtke Sina R., Weigand Julia E., Ohlenschläger Oliver, Wurm Jan‐Philip, Hammann Christian, Suess Beatrix, Wöhnert Jens. 2016. What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin‐Sensing Riboswitch Angewandte Chemie International Edition |
| Equivalence Class |
NR_all_05394.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | RIO |
| Residue | . / 101 |
| Chain | B / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 469.91 Å3 |
| Hydrophobicity | 0.101 |
| Hydrophilicity | 0.998 |
| Buriedness | 0.678 |
| Don/acc character | 1.678 |
| SiteScore | 1.145 |
| D Score | 1.022 |
| Kd | 0.33uM |