Complex 2gcv

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.10
System mass	49.37 kDa
Deposition year	2006
Molecule type	RNA
# RNA entities	1
Organism	Caldanaerobacter
RCSB PDB Entry	2gcv
Reference	Klein Daniel J., Ferré-D'Amaré Adrian R.. 2006. Structural Basis of glmS Ribozyme Activation by Glucosamine-6-Phosphate Science
Equivalence Class	NR_all_83979.2 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	MES
Residue	. / 501
Chain	C / A
Non-redundant	True
Interacting RNA chains	A/A, B/B
RNA environment detailled	other
RNA environment global	RNA/Other
RNA family chains	A/A: ribozyme, B/B: ribozyme
RNA family global	ribozyme
Volume	288.12 Å³
Hydrophobicity	0.119
Hydrophilicity	1.421
Buriedness	0.770
Don/acc character	0.673
SiteScore	1.198
D Score	0.939
Kd	—

Pocket 2

Compound	MES
Residue	. / 502
Chain	H / B
Non-redundant	False
Interacting RNA chains	A/A, B/B
RNA environment detailled	other
RNA environment global	RNA/Other
RNA family chains	A/A: ribozyme, B/B: ribozyme
RNA family global	ribozyme
Volume	175.96 Å³
Hydrophobicity	0.000
Hydrophilicity	1.567
Buriedness	0.684
Don/acc character	0.894
SiteScore	1.063
D Score	0.740
Kd	—