HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 2fcz

System information

Experimental technique	X-ray
Experimental resolution	2.01
System mass	31.84 kDa
Deposition year	2005
Molecule type	RNA
# RNA entities	1
Organism	N/A
RCSB PDB Entry	2fcz
Reference	Ennifar E.. . Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell Nucleic Acids Research

Pocket 1

Compound	RIO
Residue	. / 1024
Chain	F / A
Non-redundant	True
Interacting RNA chains	B/B, A/A
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	A/A: TAR_rna, B/B: TAR_rna
RNA family global	TAR_rna
Volume	589.96 Å³
Hydrophobicity	0.153
Hydrophilicity	1.092
Buriedness	0.684
Don/acc character	1.337
SiteScore	1.140
D Score	0.994
Kd	—

Pocket 2

Compound	RIO
Residue	. / 2024
Chain	H / B
Non-redundant	False
Interacting RNA chains	B/B, A/A
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	A/A: TAR_rna, B/B: TAR_rna
RNA family global	TAR_rna
Volume	488.43 Å³
Hydrophobicity	0.173
Hydrophilicity	1.216
Buriedness	0.680
Don/acc character	0.956
SiteScore	1.138
D Score	0.952
Kd	—

Pocket 3

Compound	RIO
Residue	. / 3024
Chain	J / C
Non-redundant	False
Interacting RNA chains	D/D, C/C
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	C/C: TAR_rna, D/D: TAR_rna
RNA family global	TAR_rna
Volume	546.40 Å³
Hydrophobicity	0.215
Hydrophilicity	1.035
Buriedness	0.679
Don/acc character	1.375
SiteScore	1.138
D Score	1.010
Kd	—

Pocket 4

Compound	RIO
Residue	. / 4024
Chain	L / D
Non-redundant	False
Interacting RNA chains	D/D, C/C
RNA environment detailled	ion, other
RNA environment global	RNA/Other
RNA family chains	C/C: TAR_rna, D/D: TAR_rna
RNA family global	TAR_rna
Volume	512.10 Å³
Hydrophobicity	0.178
Hydrophilicity	1.248
Buriedness	0.707
Don/acc character	0.989
SiteScore	1.156
D Score	0.957
Kd	—