Complex 2fcy
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.20 |
| System mass | 16.53 kDa |
| Deposition year | 2005 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2fcy |
| Reference | Ennifar E.. 2006. Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell Nucleic Acids Research |
| Equivalence Class |
NR_all_78706.4
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | NMY |
| Residue | . / 1001 |
| Chain | C / A |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: TAR_rna, B/B: TAR_rna |
| RNA family global | TAR_rna |
| Volume | 470.94 Å3 |
| Hydrophobicity | 0.195 |
| Hydrophilicity | 0.952 |
| Buriedness | 0.666 |
| Don/acc character | 2.372 |
| SiteScore | 1.146 |
| D Score | 1.029 |
| Kd | — |
| Compound | NMY |
| Residue | . / 2001 |
| Chain | H / B |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: TAR_rna, B/B: TAR_rna |
| RNA family global | TAR_rna |
| Volume | 518.27 Å3 |
| Hydrophobicity | 0.211 |
| Hydrophilicity | 1.007 |
| Buriedness | 0.695 |
| Don/acc character | 1.595 |
| SiteScore | 1.154 |
| D Score | 1.029 |
| Kd | — |