Complex 2f4s
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.80 |
| System mass | 13.81 kDa |
| Deposition year | 2005 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2f4s |
| Reference | Murray James B., Meroueh Samy O., Russell Rupert J.M., Lentzen Georg, Haddad Jalal, Mobashery Shahriar. 2006. Interactions of Designer Antibiotics and the Bacterial Ribosomal Aminoacyl-tRNA Site Chemistry & Biology |
| Equivalence Class |
NR_all_82951.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | XXX |
| Residue | . / 501 |
| Chain | C / B |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 89.18 Å3 |
| Hydrophobicity | 0.081 |
| Hydrophilicity | 0.872 |
| Buriedness | 0.572 |
| Don/acc character | 4.440 |
| SiteScore | 0.787 |
| D Score | 0.599 |
| Kd | 19uM |