Complex 2et5
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.20 |
| System mass | 16.01 kDa |
| Deposition year | 2005 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2et5 |
| Reference | Francois B.. 2005. Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding Nucleic Acids Research |
| Equivalence Class |
NR_all_71199.7
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | RIO |
| Residue | . / 54 |
| Chain | C / A |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 264.80 Å3 |
| Hydrophobicity | 0.034 |
| Hydrophilicity | 0.954 |
| Buriedness | 0.618 |
| Don/acc character | 2.732 |
| SiteScore | 0.976 |
| D Score | 0.823 |
| Kd | — |
| Compound | RIO |
| Residue | . / 51 |
| Chain | E / B |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 255.19 Å3 |
| Hydrophobicity | 0.092 |
| Hydrophilicity | 0.859 |
| Buriedness | 0.615 |
| Don/acc character | 2.392 |
| SiteScore | 0.964 |
| D Score | 0.817 |
| Kd | — |
| Compound | RIO |
| Residue | . / 52 |
| Chain | F / B |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 476.77 Å3 |
| Hydrophobicity | 0.012 |
| Hydrophilicity | 1.323 |
| Buriedness | 0.708 |
| Don/acc character | 0.941 |
| SiteScore | 1.054 |
| D Score | 0.802 |
| Kd | — |
| Compound | RIO |
| Residue | . / 53 |
| Chain | G / B |
| Non-redundant | False |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 509.36 Å3 |
| Hydrophobicity | 0.006 |
| Hydrophilicity | 1.334 |
| Buriedness | 0.712 |
| Don/acc character | 1.197 |
| SiteScore | 1.148 |
| D Score | 0.918 |
| Kd | — |