Complex 2et3
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.80 |
| System mass | 15.00 kDa |
| Deposition year | 2005 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 2et3 |
| Reference | Francois B.. 2005. Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding Nucleic Acids Research |
| Equivalence Class |
NR_all_71199.7
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | LLL |
| Residue | . / 50 |
| Chain | C / A |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 74.77 Å3 |
| Hydrophobicity | 0.050 |
| Hydrophilicity | 0.983 |
| Buriedness | 0.583 |
| Don/acc character | 3.620 |
| SiteScore | 0.710 |
| D Score | 0.490 |
| Kd | — |
| Compound | LLL |
| Residue | . / 51 |
| Chain | D / B |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/B: rRNA |
| RNA family global | rRNA |
| Volume | 101.19 Å3 |
| Hydrophobicity | 0.136 |
| Hydrophilicity | 0.859 |
| Buriedness | 0.556 |
| Don/acc character | 2.507 |
| SiteScore | 0.778 |
| D Score | 0.594 |
| Kd | — |